Maternal Hemoglobin Levels during Pregnancy and their Association with Birth Weight of Neonates

Back ground Anemia in pregnancy is associated with increased rates of maternal and perinatal mortality, premature delivery, low birth weight, and other adverse outcomes Materials and Methods A prospective study was conducted on 1405 Iranian pregnant women who delivered during 2015. Blood was collected from all the subjects to measure the hemoglobin (Hb) during 16-19 weeks, 22-24 weeks, and 34-36 weeks of gestation. According to the level of hemoglobin, it is divided into 4 groups. Group 1 Hb > 10.1 gm/100ml (control group), Group 2 Hb= 8.1-10 gm/100ml (mild anemia) Group 3 Hb= 6.5-8 gm/100ml (moderate anemia) Group 4 Hb <6.5 gm/100ml (severe anemia). After delivery, the neonates were weighted within 24 hours after birth. Maternal hemoglobin and birth weights were compared. Results The anemia prevalence was 20.2% (Hb10 g/dl), considered  as normal gave birth to heavier and normal babies (3.3 kg). The severity of anemia during three trimesters was closely associated with birth weight of newborns. Conclusion The low hemoglobin values during three trimesters of pregnancy were associated with low birth weight in Iran. The anemia can lead to intra uterine growth retardation.